» Ruu is an alien baby from the Planet Otto, who can levitate and perform telekinesis on objects, and who develops a deep love for Miyu and Kanata, likening them to his parents and often assisting and helping them. He uses his abilities at very inappropriate times causing Miyu and Kanata great trouble. Although he's still only a baby, he can understand everyone perfectly. In order to keep the others from knowing the truth about Ruu's identity, he's referred to as Miyu's little brother although Ruu will deny that and insist on calling Miyu "mama". So he believes Miyu and Kanata are his real parents but doesn't learn the truth until the end of the series.

» Wannyā, also known as Baumiao (which is a play on "Bowmeow"), is a cat-like alien babysitter pet from Planet Otto who is entrusted to take care of Ruu and can transform into all sorts of human beings, often a blond-haired man who was once the subject of Mikan's affection, and all forms of animals and objects. He develops a passionate liking for mitarashi dango and often writes about the events of the progressing day in his computerized nanny diary. Wannyā often does all the cooking and cleaning in the house.

» Often nicknamed just Chris, Christine is Miyu and Kanata's pink-haired, half-French (via her mother) and insanely wealthy classmate. She is so deeply infatuated with Kanata and becomies extremely jealous whenever she sees him with Miyu. She often expresses her rage by demonstrating her superhuman strength by picking up large objects, such as trees and desks, to throw in the process. The moment she snaps out of one of her "episodes", she'll apologize sweetly and fix whatever items she's damaged in her rampage, with tools kept in hammerspace (for example construction equipment). Her incredible jealousy is usually meant to be comical, but is sometimes used in serious situations. Chris appears completely oblivious to her supernatural powers but she appears to be timid and friendly. Coming from a very, very rich family, among her possessions are a winter lodge and a snowy mountain. Christine's parents are not seen in the anime; instead, her companion is a butler named Shikada ("Mr. Deerfield" in the English translation) who is dressed up as a deer. He has been doing this for Chris since her childhood in order to make her happy, due to her deep love for deers. Her favorite pastimes include skiing and horse riding.

» Christine's 3-year-old cousin. Momoka often drives along in her tiny toy tricycle and befriends Ruu, declaring that he's her boyfriend and that they're in a close relationship. Momoka has an odd grudge against Miyu, often calling her Madam or obā-chan, a title used for an elderly woman, which in result infuriates Miyu all the time.

» Aya is Miyu and Kanata's classmate who is a very good friend of Miyu and often goes shopping with her and Nanami. She likes school plays, which she often directs. Much to Miyu and Kanata's displeasure, some of Aya's plays or projects are extremely similar to their current life, and that's much worse when Aya develops an interest to Ruu and often features him in the plays. Aya, on occasion, has been known to start speaking French whenever she's excited.

» Nanami is Miyu and Kanata's classmate, who is a very good friend of Miyu and often goes shopping with her and Aya. Nanami is usually very playful and energetic but can sometimes be easily tired after a hard task. She also has a huge appetite.

» Santa is Kanata's best friend, who often comes up with strange ideas. He has a deep love and appreciation for old records. Miyu once thought that Santa had fallen in love with a girl, but later finds out that it was instead the girl's camera he'd fallen in love with. He has a penpal, whom he develops a liking to and vice versa. Unfortunately, she left for Germany, but not before the two meet each other in person before her departure. His name is a play on the Japanese pronunciation of "Santa Claus", though this has no direct relation to his character and may be named after the capital of New Mexico, Santa Fe.

» A budding mangaka (manga artist), Mikan often has a tangerine on her head(same goes for the rest of her relatives, even her pet Scottish fold cat) and is a very good friend of Kanata and Miyu, both of whom she often helps out and who have also helped her once with her manga. She has a handsome young brother, Mizuki Yamamura, who was the inspiration of one of the characters in her manga, and often helps her out. Mikan is often panicking because of her deadline and often comes to Kanata's house for consolation, having a few close calls to finding out Miyu and Kanata's secret. Mizuki pointed out that Mikan never gave up on her dream on becoming a manga artist, despite her father's wishes on her becoming a baker. So far, Mikan has shown to be a quite popular with her career. Although Mikan looks plain, stressed, even comical most of the time, she's actually very good-looking when with makeup or when she's relaxed. Her name is a play on that of the manga's author, Mika Kawamura. Interestingly, Mikan means " Tangerine" and Yama means "mountain" although the word Yamabuki means " orange-yellow".

» Miki is Miyu's astronaut mother who is obsessed with anything connected to outer space and is hired by NASA, along with her husband, Yu, at the beginning of the story, thus having to leave for the United States, arranging her daughter, Miyu, to live with the Saionjis. Her two childhood dreams were to have a beautiful daughter and to become an astronaut, both of which came true. She was friends with Kanata's mom ever since she was a teenager.

» Yū is Miyu's astrophysicist father who is helping his wife with her work, and is hired by NASA, along with his wife, Miki, thus having to leave for the United States, arranging his daughter, Miyu, to live with the Saionjis. He became interested in astrophysics in order to further his wife's dream in becoming an astronaut and traveling in space.

» Kanata's father, who is a monk and the patron of the Saionji household. He goes on a pilgrimage to India soon after Miyu arrives at the Saionji household.

» Kanata's late mother, who was a very good friend of Miyu's mother, Miki, and passed away when Kanata was still a child. Her remains are buried on the Saionji Temple grounds.

» Miyu and Kanata's teacher, who is talented in numerous skills, ranging from cooking to ninja training.

» Seiya is a blonde-haired alien who visits Earth and takes a liking to Miyu, often disguising as Kanata to get close to her. He has a sister, Rui, who saved him once from being sucked into a worm hole, and has had a sheltered childhood.

» Rui is Seiya's older sister, who greatly cares for Seiya, saving him once from being sucked into a worm hole.

» The eccentric principal of Miyu and Kanata's school, who is extremely fond of monkeys, bananas and video games, especially monkey-based ones, his fascination with the creatures stemming from his deep friendship with his monkey,, from whom he was disunited with in his childhood due to the monkey having been sucked into a worm hole, but with whom he's later reunited, thanks to the help of Miyu, Kanata, Ruu and Wannya. All forms of monkey dolls and replicas adorn his office, where he's often found playing video games, and has sometimes even set the themes of school meets to monkey-based ones.

» A alien rabbit that becomes Ruu's pet after an accident falling from a truck from Outer Space later in the series. In the manga, he's all white and debuts late in volume 7.

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